Neorecormon For Anemia Marina 3.75

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The difference that one can find between a brand medication and a generic lies in the name, shape and price.
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Elliott: Investigation of the effects of altered receptor binding activity on the clearance of erythropoiesis-stimulating proteins: Nonerythropoietin receptor-mediated pathways may play a major role.

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Use of thrombopoietic growth factors in acute leukaemia.

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There exists a need to develop methods of reducing the viscosity of a formulation containing high concentrations of protein, and a need for resulting reduced viscosity formulations.

IU once weekly for 16 weeks with or without concomitant intravenous iron supplementation.

Results from the First Decade of Research Conducted by the Research on Adverse Drug Events and Reports (RADAR) Project.

Immunologically mediated PRCA is by far the commonest cause in adults, particularly since 1998, when a marked increased incidence of PRCA was noted in chronic renal failure patients receiving subcutaneous (SC) recombinant erythropoietin (rEpo).

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Managing chemotherapy-induced anemia with biosimilar epoetin α is consistently cost efficient over treatment with originator epoetin α, epoetin β, and darbepoetin α under both fixed and weight-based dosing scenarios.

Treating anemia early in renal failure patients slows the decline of renal function: a randomized controlled trial.

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Clinicians need comprehensive information on biosimilars, and biopharmaceuticals in general, to make informed treatment decisions.

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Subsequent analyses of outcomes in CHOIR showed shorter times to progression of kidney disease and higher rates of renal replacement therapy and death among patients randomized to the higher Hb target.

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Epoetin alfa and darbepoetin are the ESAs approved for use in treatment of cancer-related anemia; pegylated epoetin beta is not FDA approved for this indication, as studies have demonstrated increased mortality and no significant improvement in clinical outcomes.

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Although some biologics are regulated under the Federal Food, Drug, and Cosmetic Act (FDCA) for historical reasons, and are, therefore, candidates for generic production through section 505(j), an Abbreviated New Drug Application (ANDA), or through 505(b)(2), using data from previously approved innovator biologics to make claims of safety and effectiveness, there is no abbreviated path for replica or closely similar follow-on products for biologics under the PHS Act.

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